We are developing a computational method to analyze proteomics data for the detection of junction-specific peptide and alternative splicing. In details, we will
- Identify the human junction-specific peptides using information from the exon database we created;
- Assign confidence for junction-specific peptides using the fragment ions in MS/MS spectra;
- Modeling alternative splicing using junction-specific peptide information
Weihong Xu and Soyoung Ryu